Cascading call National Center 3-spoke 2 Cancer- Sapienza

July 5, 2024

FORM FACILITATION

Contribution/Repayable fund

REGIONS

Piedmont, Lombardy, Valle d'Aosta/Vallée d'Aoste, Liguria, Abruzzo, Molise, Basilicata, Calabria, Campania, Puglia, Sicily, Trentino-Alto Adige/Südtirol, Veneto, Sardinia, Tuscany, Friuli-Venezia Giulia, Emilia- Romagna, Umbria, Marche, Lazio

SECTOR

Health, Other services

ALLOWED EXPENSE

300000 €

INCENTIVE STATUS

CLOSED

OPENING DATE

CLOSING DATE

May 3, 2024
June 3, 2024

NOTES

No additional notes
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Things

The entity managing this Call is Sapienza University of Rome, as Leader of Spoke 2 of the National Center "National Center for Gene Therapy and Drugs based on RNA Technology". Specifically, Spoke 2 aims to develop RNA-based therapies for the treatment of tumors and metastases as part of the CN RNA & Gene Therapy research program. The main activities are focused on the identification of molecular targets in human tumors that can be regulated by inhibitory RNAs, such as ASO or si RNA, the development of strategies to increase tumor immunogenicity using therapeutic RNAs, the identification and analysis of diagnostic, prognostic and treatment response biomarkers and the development of pipelines for anti-tumor vaccines. 

Who is it aimed at?

All Beneficiaries must be either Companies or Research Organisations. The partners of the “National Center for Gene Therapy and Drugs based on RNA Technology” project and the members of the “National Research Center – Development of Gene Therapy and Drugs with RNA Technology” Foundation cannot be beneficiaries of the funding provided for by this notice. 

What does it predict

Sapienza University of Rome (hereinafter also just "Sapienza") as leader of Spoke 2 with this Public Notice intends to implement the "cascade calls" (financial support to third parties - FSTP or cascade funding) envisaged by the Centro project National “National Center for Gene Therapy and Drugs based on RNA Technology” financed by the MUR, financing Research and Development and Collaborative Projects, i.e. carried out by Companies and Research Organizations in Effective Collaboration with each other. The funded Collaborative R&D Projects must be consistent with the themes of the National Center "National Center for Gene Therapy and Drugs based on RNA Technology", the specific R&D objectives of Spoke 2, limited to WP 2.1, WP 2.2 and WP 2.3. 

Objective – Purpose

Innovation and research

Form – Facilitation

Contribution/Repayable fund

Minimum Allowable Expenditure

300000 €

Maximum Allowable Expenditure

600000 €

Allowed Costs

Buildings and land, Professional training, Personnel costs, Raw materials, consumables and goods, Services, patents and licenses, General expenses/other charges, Plant/Machinery/Equipment

Minimum concession that can be granted

300000 €

Maximum grantable benefit

600000 €
Subject type
Company, University/Research Institution, Public Institution

Dimension

Medium Enterprise, Large Enterprise, Small Enterprise

Activity sector

Health, Other services

ATECO

All economic sectors eligible to receive aid

Regions

Piedmont, Lombardy, Valle d'Aosta/Vallée d'Aoste, Liguria, Abruzzo, Molise, Basilicata, Calabria, Campania, Puglia, Sicily, Trentino-Alto Adige/Südtirol, Veneto, Sardinia, Tuscany, Friuli-Venezia Giulia, Emilia- Romagna, Umbria, Marche, Lazio

Other features

Spoke 2 is organized into four main Work Packages (WP): - WP 2.1: is focused on the identification of new molecular targets for the development of innovative RNA therapies and biomarkers of disease and follow-up of patients affected by tumors; - WP 2.2: is dedicated to the validation of therapeutic targets and identified biomarkers;- WP 2.3: is dedicated to the development of innovative anti-tumor vaccines, innovative therapies to increase the immunogenicity of tumors and the design of new combined therapies;- WP 2.4: dedicated to increase the transferability of the results obtained in WP 2.1-2.3 and develop synergies and networks within the project.

Managing entity

University of Rome La Sapienza

Primary regulatory basis

MUR Directorial Decree n. 3138 of 16 December 2021 and subsequent addition to DD n. 3175 of 18 December 2021, registered at the Court of Auditors on 15/01/2022 n. 100

Implementation measure

MUR Directorial Decree n. 3138 of 16 December 2021 and subsequent addition to DD n. 3175 of 18 December 2021, registered at the Court of Auditors on 15/01/2022 n. 100

Incentive allocation

2400000 €

Reference site

https://www.uniroma1.it/it/notizia/e-online-il-bando-cascata-sapienza-pnrr-centro-nazionale-3-national-center-gene-therapy-and

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